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Yasushi Sakata Selected Research

Diastolic Heart Failure

6/2014Relation of risk factors with response to carvedilol in heart failure with preserved ejection fraction - a report from the Japanese Diastolic Heart Failure Study (J-DHF).
10/2008Difference of clinical characteristics between hypertensive patients with and without diastolic heart failure: the roles of diastolic dysfunction and renal insufficiency.
5/2008Beneficial effects of bisoprolol on the survival of hypertensive diastolic heart failure model rats.
2/2007Elevated cardiac tissue level of aldosterone and mineralocorticoid receptor in diastolic heart failure: Beneficial effects of mineralocorticoid receptor blocker.
2/2007Therapeutic effects of angiotensin II type 1 receptor blocker at an advanced stage of hypertensive diastolic heart failure.
2/2005ACE inhibitor and angiotensin II type 1 receptor blocker differently regulate ventricular fibrosis in hypertensive diastolic heart failure.
3/2004AT1 receptor blocker added to ACE inhibitor provides benefits at advanced stage of hypertensive diastolic heart failure.
1/2004Elevation of plasma brain natriuretic peptide is a hallmark of diastolic heart failure independent of ventricular hypertrophy.
9/2003Angiotensin II type 1 receptor blockade prevents diastolic heart failure through modulation of Ca(2+) regulatory proteins and extracellular matrix.
3/2003Temocapril prevents transition to diastolic heart failure in rats even if initiated after appearance of LV hypertrophy and diastolic dysfunction.
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Yasushi Sakata Research Topics

Disease

101Heart Failure
11/2022 - 02/2002
50Atrial Fibrillation
12/2022 - 01/2014
25Fibrosis (Cirrhosis)
01/2022 - 07/2002
16Myocardial Infarction
02/2022 - 08/2006
15Hemorrhage
06/2022 - 02/2017
15Cardiovascular Diseases (Cardiovascular Disease)
01/2022 - 03/2003
14Cardiomyopathies (Cardiomyopathy)
07/2022 - 03/2016
13Diastolic Heart Failure
06/2014 - 04/2002
12Hypertension (High Blood Pressure)
01/2022 - 02/2002
12Left Ventricular Dysfunction
01/2021 - 05/2004
11Stroke (Strokes)
06/2022 - 01/2014
9Hypertrophy
01/2022 - 07/2002
8Aortic Valve Stenosis (Aortic Stenosis)
12/2022 - 05/2011
8Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
07/2022 - 01/2012
8Thrombosis (Thrombus)
01/2022 - 01/2016
8Pulmonary Hypertension
01/2021 - 08/2010
7Diabetes Mellitus
01/2022 - 05/2011
7Neoplasms (Cancer)
03/2021 - 03/2016
7Ischemia
01/2021 - 01/2007
7Inflammation (Inflammations)
07/2020 - 01/2016
6Infections
12/2022 - 01/2017
6Embolism (Embolus)
06/2022 - 04/2020
6Death (Near-Death Experience)
01/2022 - 01/2016
6Cardiomegaly (Heart Hypertrophy)
01/2021 - 05/2009
6Infarction (Infarctions)
01/2019 - 06/2002
5Ventricular Tachycardia
07/2022 - 05/2015
5Body Weight (Weight, Body)
03/2022 - 01/2008
5Peripheral Arterial Disease
01/2022 - 09/2018
5Mitochondrial Diseases (Mitochondrial Disease)
10/2021 - 02/2017
5Renal Insufficiency (Renal Failure)
04/2021 - 10/2008
5Heart Diseases (Heart Disease)
03/2021 - 07/2004
5Hypoxia (Hypoxemia)
01/2021 - 02/2015
5Pulmonary Arterial Hypertension
01/2021 - 06/2009
4Hypertriglyceridemia
02/2022 - 02/2018
4Neointima
08/2021 - 01/2019
4Coronary Artery Disease (Coronary Atherosclerosis)
02/2021 - 05/2004
4Pathologic Constriction (Stenosis)
09/2020 - 11/2018
4Atherosclerosis
10/2019 - 01/2018
4Systolic Heart Failure
05/2008 - 03/2003
3Acute Coronary Syndrome
03/2022 - 02/2021
3Obesity
01/2022 - 10/2008
3Tricuspid Valve Insufficiency (Insufficiency, Tricuspid Valve)
04/2021 - 11/2017
3Hypotension (Low Blood Pressure)
01/2021 - 06/2013
3Type 2 Diabetes Mellitus (MODY)
01/2021 - 04/2016
3Malnutrition (Nutritional Deficiencies)
01/2021 - 01/2019
3Dyslipidemias (Dyslipidemia)
06/2020 - 06/2018
3Abdominal Aortic Aneurysm
02/2020 - 01/2014
3Myocarditis (Carditis)
01/2020 - 01/2016
3Takayasu Arteritis (Arteritis, Takayasu's)
01/2020 - 01/2013

Drug/Important Bio-Agent (IBA)

17Brain Natriuretic Peptide (Natrecor)FDA Link
11/2022 - 01/2004
15Proteins (Proteins, Gene)FDA Link
01/2022 - 09/2003
14AnticoagulantsIBA
10/2022 - 09/2017
10Pharmaceutical PreparationsIBA
07/2021 - 08/2015
8SaltsIBA
12/2013 - 04/2002
7C-Reactive ProteinIBA
12/2022 - 01/2018
7Biomarkers (Surrogate Marker)IBA
03/2021 - 01/2016
6SteroidsIBA
02/2022 - 09/2010
6Indicators and Reagents (Reagents)IBA
01/2022 - 02/2002
6Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
01/2019 - 03/2003
6CollagenIBA
08/2015 - 07/2002
5pro-brain natriuretic peptide (1-76)IBA
11/2022 - 07/2020
5CreatinineIBA
03/2022 - 10/2008
5Hemoglobins (Hemoglobin)IBA
03/2022 - 10/2008
5Triglycerides (Triacylglycerol)IBA
01/2022 - 05/2011
5CytokinesIBA
01/2016 - 12/2004
4Warfarin (Coumadin)FDA LinkGeneric
10/2022 - 08/2010
4(R)-2-(3-((benzoxazol-2-yl-d4 (3- (4- methoxyphenoxy- d7)propyl)amino)methyl)phenoxy) butanoic acidIBA
02/2022 - 02/2018
4CalciumIBA
01/2022 - 04/2013
43-Iodobenzylguanidine (Iobenguane)IBA
01/2022 - 06/2015
4LipidsIBA
08/2021 - 04/2016
4omega-Chloroacetophenone (Mace)IBA
03/2021 - 03/2020
4HDL CholesterolIBA
01/2021 - 05/2011
4Glucose (Dextrose)FDA LinkGeneric
01/2021 - 03/2016
4Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
03/2020 - 05/2011
4CateninsIBA
01/2020 - 07/2015
4tocilizumab (atlizumab)FDA Link
01/2020 - 09/2010
4DNA (Deoxyribonucleic Acid)IBA
06/2019 - 01/2011
4Therapeutic UsesIBA
02/2007 - 03/2003
3Sodium-Glucose Transporter 2 InhibitorsIBA
01/2022 - 04/2016
3CholesterolIBA
01/2022 - 01/2020
3CanagliflozinIBA
01/2022 - 04/2016
3Vasodilator Agents (Vasodilators)IBA
05/2021 - 09/2012
3Natriuretic PeptidesIBA
03/2021 - 01/2021
3Doxorubicin (Adriamycin)FDA LinkGeneric
01/2021 - 11/2005
3Serum AlbuminIBA
01/2021 - 08/2015
3Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
07/2020 - 01/2019

Therapy/Procedure

40Therapeutics
02/2022 - 05/2007
29Catheter Ablation
02/2022 - 01/2012
18Heart-Assist Devices
12/2022 - 01/2011
14Stents
01/2022 - 01/2016
10Heart Transplantation (Grafting, Heart)
01/2022 - 01/2012
8Transcatheter Aortic Valve Replacement
12/2022 - 12/2012
8Transplantation
01/2021 - 01/2015
6Percutaneous Coronary Intervention
12/2021 - 06/2016
4Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
07/2022 - 12/2015
4Palliative Care (Palliative Therapy)
01/2021 - 01/2018
4Endovascular Aneurysm Repair
02/2020 - 01/2014
3Renal Dialysis (Hemodialysis)
12/2022 - 01/2019
3Cardiac Rehabilitation
03/2022 - 01/2021
3Glycemic Control
01/2021 - 04/2016